FIB/SEM Image Processing and Quantification
Avizo Fire data visualization and analysis software addresses the full scope of Focused Ion Beam (FIB)/Scanning Electron Microscope (SEM) 2D/3D imaging applications, such as electronics and semiconductors failure analysis, nanomanufacturing, materials characterization, or rock and geomaterials properties analysis.
FIB/SEM image analysis steps may include 2D alignment of slices, shadow correction, image filtering, high-throughput feature identification and segmentation, feature measurements for statistical analysis, geometric model reconstruction, characterization and numerical simulation.
Most images are extracted from the Tin Whisker and Hillock Case Study [1]

3D image reconstruction
As raw image stack is not directly interpretable in 3D, specific reconstruction is required for FIB/SEM, including:
- Multi-functional Alignment
- Foreshortening correction
- Shear/drift correction
- Shadowing correction

3D data exploration
- High-end interactive 3D navigation
- Direct volume rendering with real-time color/opacity mapping
- Orthogonal, oblique, cylindrical, and curved slicing
- Contouring and iso-surface extraction
- Interactive measurement data probing tools
- Accelerated large data management

Image processing and segmentation, feature extraction
Avizo Fire provides a wide range of tools to identify, separate, and analyze multiple phases, grains, porosities or interfaces:
- Advanced image filtering
- Thresholding and auto-segmentation, object separation, automatic labeling
- Region growing, snakes, interpolation, wrapping, smoothing
- Advanced mathematical morphology operators, including watershed, basins, multi-phase segmentation, phase interfaces, porosities
- Interactive segmentation editor with multi-function toolbox
- Medial axis skeletonization
- Phases boundaries extraction

Data registration and fusion
- Multiple data channels can be combined for enhanced segmentation or compositional analysis e.g. BSE, EDX/EDS, EBSD, x-ray spectroscopy, etc.
- Multiple modalities and scales can be combined for correlative analysis e.g. micro-CT, nano-CT, AFM, etc.
- Experimental images and simulation results can be combined
- Registration of images or geometric data

Advanced statistical analyses and numerical characterization
- Over 70 built-in measurements, incl. particle count, volumes, areas, perimeters, aspect ratios, orientations, etc.
- Morphometric measures such as fractal roughness, degree of anisotropy, propagation
- User-defined measures
- Results viewer with spreadsheet tool and charting with export to .CSV
- Automatic individual feature measurements, 3D localization, and spreadsheet selection, automated statistics, distributions graphs
- Feature filtering using any measurement criterion
- Advanced pre-/post-processing tools for numerical simulation of physical properties, whether mesh-based FEA/CFD solvers, network simulations, direct image-based simulations, Lattice Boltzmann solvers, etc.

Extensible workflows
Easily integrate Avizo in your environment and workflow:
- MATLAB® bridge: live bidirectional communication between Avizo workspace and MATLAB compute engine
- Flexible workflow, automation, TCL scripting for interactive or batch execution of routine tasks
- Customize Avizo by expanding it using the Xpand extension

Presentation, sharing and reporting
- Unique high quality visualization
- Integrate images, geometric models, measurements, and simulations
- Markup with textual annotations, legends, histograms, and 2D plots
- Advanced animation creation
- Export spreadsheets, 3D models, images, and movies
- Support for advanced presentation and collaborative environments (immersive theaters, VR systems, etc.) with the XScreen extension
[1] Marsh M, Williams M, Moon K-W, and Boettinger W. "Image Processing and Quantification in FIB Reconstructions. Tin Whisker and Hillock Case Study". Microscopy and Microanalysis. 2010. 16 (S2), 1832-1833.